The IGH/CCND1 product consists of probes, labeled in green, covering the Constant, J, D and Variable segments of the IGH gene, and CCND1 probes labeled in red. The CCND1 probe mix contains a 267kb probe centromeric to CCND1 gene, covering the region between the D11S1100 and the D11S4095 markers, and a second 223kb probe covering the telomeric end of CCND1 gene.
It was very important for us to have more consistent results with our probes — easy-to-read bright signals and a range of vial sizes, which is much more cost-effective. It also was critical to upgrade our pretreatment kit to expedite the analysis of FFPE samples. We can now complete the process in about 90 minutes.
Janet Cowan, PhD
Director of the Cytogenetics Laboratory, Tufts Medical Center, USA
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