Dr. Stephen Moore will share his experience utilising OGT's CytoSure® chromosomal microarrays in various tumour types. Specifically, he will highlight the different applications of the single nucleotide polymorphism (SNP) track beyond oligonucleotides confirmation.
Read and download the Customer presentationThis white paper, first published in Genomic Medicine, demonstrates that OGT’s CytoSure Constitutional v3 array, with an enhanced targeted exon-level resolution design, offered a significant increase in reporting rate (4.49%) for developmental disorder (DD) research, compared to traditional arrays.
Read and download the White paperCytoSure arrays offer robust copy-number detection with high resolution – detecting CNVs of a few hundred base pairs at the single-exon level. However, a number of different factors need to be taken into account when designing microarrays to make sure that they offer robust performance across the targeted regions. Learn more about the process that we undertake to make sure our arrays perform the best they possibly can.
Read and download the Application noteThis application note illustrates the use of the InnoScan 710 scanner and Mapix with a range of OGT CytoSure cytogenetic array formats.
Read and download the Application noteLora Bean provides valuable insights into the use of microarrays and NGS in parallel for CNV detection. While CNV calls from NGS data are becoming increasingly popular, they must be confirmed due to the significant false positive rate associated with them.
Read and download the Customer presentationThis whitepaper from Dominic McMullan, West Midlands Regional Genetics Laboratory, Birmingham, UK, demonstrates that the CytoSure Constitutional v3 microarray can detect variants not detectable by other microarray platforms.
Read and download the White paperIn this white paper, Kris Van Den Bogaert describes how the most current microarray technology is set to increase the detection of disease-relevant variants following a validation and implementation programme at the Department of Human Genetics, University Hospitals Leuven, Belgium.
Read and download the White paperMadhuri Hegde expands on her work with OGT combining NGS, microarrays — including OGT’s CytoSure® Disease-Focused Research arrays — and an all-inclusive genomic data interpretation platform for comprehensive analysis of genetic disorders.
Read and download the Customer presentationDom McMullan discusses the implementation of the CytoSure® Constitutional v3 microarray in the NHS laboratory, and how it facilitated cost-effective, evidence-based analysis of large populations.
Read and download the Customer presentationKris Van Den Bogaert discusses the evaluation of the CytoSure® Constitutional v3 microarrays in prenatal and postnatal research.
Read and download the Customer presentationDr Tracey Lewis delves into the benefits of combining the study of copy number variations (CNVs) and single nucleotide variations (SNVs) for enhanced mutation detection across a range of genetic conditions.
Read and download the Customer presentationIn this white paper, genetic scientists Dr Tracey Lewis and Dr Emily Farrow discuss how customisable, exon focused array designs complement next generation sequencing (NGS) for clinical genetic research.
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