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Product summary

  • Chromosomes
    17
  • Labels
  • Disease focus Constitutional
  • Regulatory status Analyte specific reagent. Analytical and performance characteristics are not established.
LPU019 Map (Smith Magenis & Miller Dieker).
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Chromomaps

17p13.3 (LIS1) / 17p11.2 (RAI1)

FISH chromosome map showing probes targeting regions associated with Smith-Magenis (RAI1 gene) and Miller-Dieker syndromes. Expand image.

Overview

Probe specification

  • LIS1 (PAFAH1B1), 17p13.3, Red
  • RAI1, 17p11.2, Green

The Miller-Dieker (LIS1) probe is 117kb, labeled in red and covers the entire LIS1 (PAFAH1B1) gene. The Smith-Magenis (RAI1) probe is 158kb, labeled in green and covers the centromeric end of the RAI1 gene and includes the D17S258 marker. The two unique sequences act as control probes for each other and allow identification of chromosome 17.

Fluorescence in situ hybridization (FISH) microscope image of the CytoCell Smith-Magenis (RAI1)/Miller-Dieker Region probe.

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What our customers say

I first came across CytoCell FISH probes in a previous lab I worked in and I was struck by the quality of the products. Since this time, I have been recommending and introducing CytoCell probes across all application areas — now they are the primary FISH probes used in our lab. They have an excellent range of products and their ready-to-use reagent format saves considerable time.

Elizabeth Benner, Medical Technologist, University of Arizona Health Network, USA.

Elizabeth Benner

Medical Technologist, University of Arizona Health Network, USA

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FISH resources & support

Learn about the basics of FISH, NGS and arrays.

FISH basics

Read scientific literature for FISH, NGS and arrays.

FISH scientific literature